A series of low pressure systems along a frontal boundary will trigger plenty of rain and severe thunderstorms across the South through Saturday.
To complicate matters, an unusually strong disturbance aloft will swing down through the Mississippi Valley and into the Southeast from Saturday to Sunday. This sytem has already dumped significant snow over parts of South Dakota and Nebraska on Friday. This will lead to wintry weather across a significant portion of the South this weekend.
Periods of rain and thunderstorms will impact the Tennessee Valley and Deep South through Saturday, with heavy flooding rainfall from northern Mississippi to the Carolinas.
Across areas from north-central Mississippi, across central and northern Alabama and Georgia, into the Carolinas, 2 to 4 inches of rain will be possible, with isolated higher amounts. Flooding and flash flooding is likely.
Severe thunderstorms from east Texas to Alabama will shift to southern Alabama and Georgia, north Florida and South Carolina Saturday. Large hail, damaging winds, and tornadoes are possible. Locally heavy rainfall can also be expected.
The aforementioned disturbance aloft will allow rain to change to snow by late Saturday from eastern Arkansas and northern Mississippi. Sunday will feature snow spereading from northern Georgia to the Carolinas. Many locations will see several inches of snow. The western and central Carolinas and southwest Virginia may see a major snowfall by Sunday night and early Monday.
While all of that is going on, snow, sleet and rain will ride up the Eastern Seaboard on Sunday. The Washington, D.C., to Philadelphia corridor will see little, if any, accumulation. New York City may see from 1 to 3 inches of snow and sleet. Boston, or areas just north and west of Boston, may see slightly higher snowfall amounts.
Monday into Tuesday, the immediate East Coast from the Outer Banks to Cape Cod will see snow Monday as the Southeast storm moves up the coast. Cape Cod could see the heaviest snow but snow may mix with sleet at times.