It would the final mission for a spacecraft that had traveled into space over three dozen times, and it blasted off on this day in history.
Originally planned for a launch in 2010 but pushed back to technical issues, STS-133 would be the final launch for the Space Shuttle Discovery.
It took off from Cape Canaveral on February 24th, 2011. It carried several payloads into space along with its crew of six astronauts.
Those payloads included the Leonardo module and Express Logistics Carrier for the International Space Station.
After two weeks in space, Discovery would land for the final time on March 9th, 2011.
The Discovery is now on display at the Smithsonian National Air and Space Museum.