The grand opening of the Nature Gallery is set for Saturday, the same day as the downtown Christmas Festival in Dothan.
One of a kind paintings and prints will be for sale, as well as exotic gifts like candles and jewelry.
There is also a room upstairs that artists may eventually be able to use to hold classes in.
Owner, Gretchen Schulz, says she is happy to support local artists and bring a new business downtown.
"I hope everyone comes in and enjoys my shop just as much as I do. You get a wonderful feeling when you walk in and I just hope everyone else feels the same way," said Schulz.
There will be other businesses open during Saturday's downtown festival including Foster Street Cafe, Bistro, and District.