It happened around 11:15 a.m. Monday morning on Highway 431 in Newville.
Henry County coroner Derek Wright identifies the victim as 46-year-old Debra Anise Askew of Columbus.
He says she slowed or stopped her car behind a truck that was stopped in the highway when her car was rear-ended by another car.
The impact knocked Askew's car into the truck. She was pronounced dead at the scene. The driver of the other car had minor injuries. Wright says no one in the truck appeared to be injured.