The Bay County Sheriff's Department has called in dozens of volunteers to help in the search for Pam Biggers.
They say Biggers went into her Panama City hotel room Sunday night and that was the last anyone saw of her.
Investigators say the 52-year-old arrived in Panama City with a friend and checked into the La Quinta Inn on Thomas Drive on Sunday.
Deputies say sometime between 7 pm Sunday night and Monday morning, she went missing.
She left behind all her belongings: purse, cell phone, even her car.
She was last seen wearing a white sweater with black pin-striped pants.
There are more than 40 volunteers looking for her.
Anyone with information about Pamela Biggers should call the Bay County Sheriff’s office at (850) 747-4700.