The Army has incinerated the last of more than 42,000 sarin-filled rockets stored in bunkers at Anniston Army Depot.
Officials with the Chemical Waste Disposal Facility said the weapons incinerator destroyed the final M55 rocket filled with the lethal nerve agent sarin, also called GB, last Friday.
The Anniston depot still includes tens of thousands of GB-filled artillery shells, plus weapons filled with the nerve agent VX and mustard gas.
The next phase of operations, involving artillery shells filled with sarin, is expected to begin in December.
While opponents claim the incinerator is a safety threat to both the community and workers, the military said employees have worked more than six million hours without losing a day of work to injury.
The incinerator began destroying the Cold War-era weapons in August 2003.
All the weapons stored at the depot are expected to be destroyed over the next six years.