Reports say 44-year-old Carl James Bourque, of Marietta, and 31-year-old Bobbie Jean Colston, of Woodstock are being held in the Cobb County Adult Detention Center on felony theft charges.
Police are looking for a third suspect, but have not released details on their identity.
An employee at The Hope Center in Woodstock reported the trailer missing Wednesday, and authorities arrested the couple Thursday evening.
A tipster saw the stolen trailer parked at a hotel in Kennesaw and called Cobb County Police.
Authorities say two off the five cribs have been recovered.
Woodstock is about 30 miles north of Atlanta.
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