Alabama has some of the strongest laws in the country against synthetic drugs.
On the street these so-called designer drugs are called spice and law enforcement says they're targeted at children.
Two years ago, two Houston County men were arrested for having cupcakes filled with spice.
Now the DEA is heading a nationwide operation known as Project Synergy, to crack down on synthetic drugs.
Substance abuse specialists say they're easier to get a hold of than regular marijuana.
They say synthetic marijuana is much stronger.
It can increase your heart rate, which can lead to a heart attack, stroke, hallucinations and even suicidal thoughts.
Experts say manufacturers are constantly changing the make-up of each batch, so you never really know what you are putting into your body.
"It's really dangerous because one package to another is totally different because someone is spraying it on and just because you did one and you had a good trip you could have a bad trip and it can be the end of your life," said Judy Guiler from The Prevention Project.
The ban on synthetic drugs in Alabama is flexible to prevent manufacturers from changing the chemical make-up of the drugs to get around existing laws.
Wednesday, more than 38 people were arrested And more than 200 pounds of synthetic drugs were seized in Alabama.