Sheriff's officials say they responded to a call about a naked man who entered a home and threatened its occupants Sunday night.
Police say the man fled and tried entering another house when officers tried subduing him.
Phenix City police assisted sheriff's deputies in a struggle authorities say lasted more than 10 minutes.
Authorities say the man was combative even after deputies used a Taser to try subduing him.
The Opelika-Auburn News reports the man passed out and was taken to the Jack Hughston Medical Facility where he was pronounced dead.
Sheriff Jay Jones has requested the Alabama Bureau of Investigation to probe the incident.