The Florida Highway Patrol says more than 20 people were killed over the Labor Day holiday period.
During the official holiday driving period that started Friday and ended Monday, the FHP investigated more than 1,300 collisions.
About 180 drivers were charged with DUI and 23 people were killed.
The majority of those killed were either motorcyclists or pedestrians.
More than 7,000 speeding citations were issued and another 1,300 were issued for seat belt and child restraint violations.
In Alabama, state troopers say at least 5-people died in traffic accidents during the holiday travel period.
Troopers said three of the fatalities occurred in Baldwin County.
The victims included two bicyclists who were hit by a pickup truck Monday morning near US 31.
Other deadly wrecks occurred in Sumter and Pike counties.