A traffic stop on Interstate 20 and 59 led to the seizure of approximately $750,000 in cocaine.
Tuscaloosa County Sheriff Ted Sexton said the drugs were found in a late model van after the driver was stopped for a traffic violation.
A sheriff's deputy called for assistance after finding a small amount of marijuana in the van.
A drug dog alerted officers who found the cocaine in two separate hidden compartments.
The driver, whose name was withheld, was turned over to federal drug agents and criminal charges are pending.
The justice department says I-20 is one of the main highways used to transport cocaine coming from Mexico and South America.